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CareHub by OpenPHR • 128 Restored Condition Guides

Clinical Knowledge Hub

Comprehensive, patient-facing medical summaries outlining the standard of care, over-the-counter and prescribed pharmaceutical interventions, and active clinical trials across Neurology and Dermatology.

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Showing 128 of 128 restored CareHub clinical guides
Neurology4 min read

Acanthosis Nigricans

Clinical guidelines for managing hyperpigmented velvety plaques, evaluating insulin resistance and IGF-1 receptor parameters, and reviewing topical...

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Dermatology4 min read

Acne Vulgaris

Clinical guidelines for managing severe breakouts, preventing scarring, and exploring advanced therapies.

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Neurology4 min read

Acoustic Neuroma

Clinical guidelines for managing vestibular schwannomas, evaluating cerebellopontine angle MRI scans, and reviewing surgery versus stereotactic rad...

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Dermatology4 min read

Actinic Keratosis

Clinical guidelines for managing precancerous skin lesions, field therapies, and cryosurgery.

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Dermatology4 min read

Alopecia Areata

Clinical guidelines for managing autoimmune hair loss, evaluating follicular immune privilege collapse, and reviewing JAK inhibitor and local stero...

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Neurology5 min read

Alzheimer's Disease

Clinical guidelines for managing cognitive decline, amyloid-targeting therapies, and care planning.

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Dermatology4 min read

Alzheimer's Disease

Clinical guidelines for managing neurodegenerative cognitive decline, diagnostic biomarkers, and emerging disease-modifying therapies.

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Neurology4 min read

Amyotrophic Lateral Sclerosis

Clinical guidelines for managing motor neuron degeneration, evaluating glutamate excitotoxicity and TDP-43 pathology, and reviewing disease-modifyi...

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Dermatology4 min read

Aphasia

Clinical guidelines for managing language impairment, evaluating Broca's and Wernicke's localization parameters, and reviewing speech-language and ...

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Neurology4 min read

Asthma

Clinical guidelines for managing airway inflammation and severe exacerbations.

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Neurology4 min read

Attention-Deficit/Hyperactivity Disorder (ADHD)

Clinical guidelines for managing inattention, hyperactivity, and executive dysfunction across the lifespan.

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Dermatology4 min read

Basal Cell Carcinoma

Clinical guidelines for managing the most common skin cancer, evaluating Hedgehog pathway mutations, and reviewing surgical Mohs and topical therap...

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Neurology4 min read

Benign Paroxysmal Positional Vertigo (BPPV)

Clinical guidelines for managing otoconia displacement, performing Dix-Hallpike diagnostic testing, and executing Epley repositioning maneuvers.

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Dermatology4 min read

Bipolar Disorder

Clinical guidelines for managing mania, bipolar depression, and mood stabilization therapies.

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Neurology4 min read

Borderline Personality Disorder

Clinical guidelines for managing emotional dysregulation, self-harm, and Dialectical Behavior Therapy.

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Dermatology4 min read

Bullous Pemphigoid

Clinical guidelines for managing subepidermal blistering in older adults, evaluating BP180 and BP230 autoantibodies, and reviewing topical and syst...

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Neurology5 min read

CADASIL

Clinical guidelines for managing hereditary stroke disorders, evaluating NOTCH3 gene mutations, temporal pole MRI parameters, and reviewing antipla...

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Dermatology4 min read

Carpal Tunnel Syndrome

Clinical guidelines for managing median nerve compression, wrist splinting, physical therapy, and surgical release options.

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Neurology4 min read

Celiac Disease

Clinical guidelines for managing gluten-induced enteropathy, mucosal healing, and strict dietary adherence.

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Dermatology4 min read

Charcot-Marie-Tooth Disease

Clinical guidelines for managing inherited neuropathies, evaluating PMP22 duplication, axonal and demyelinating electrodiagnostics, and reviewing p...

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Neurology4 min read

Chronic Inflammatory Demyelinating Polyneuropathy (CIDP)

Clinical guidelines for managing chronic peripheral nerve demyelination, evaluating NF155 and CNTN1 IgG4 autoimmunity, and reviewing IVIG, steroids...

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Neurology4 min read

Chronic Obstructive Pulmonary Disease

Clinical guidelines for managing dyspnea, exacerbations, and lung function decline in COPD.

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Dermatology4 min read

Cluster Headaches

Clinical guidelines for aborting acute cluster attacks, establishing preventive regimens, and managing trigeminal autonomic symptoms.

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Neurology4 min read

Complex Regional Pain Syndrome

Clinical guidelines for managing neurogenic inflammatory pain, evaluating Budapest clinical criteria, and reviewing physical therapy and neuromodul...

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Dermatology4 min read

Contact Dermatitis

Clinical guidelines for identifying triggers, patch testing, and restoring the skin barrier.

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Dermatology4 min read

Creutzfeldt-Jakob Disease

Clinical guidelines for managing rapidly progressive neurodegenerative disorders, evaluating prion protein conformational changes, RT-QuIC and MRI ...

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Neurology4 min read

Crohn's Disease

Clinical guidelines for managing Inflammatory Bowel Disease (IBD), mucosal healing, and immune modulation.

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Dermatology4 min read

Cutaneous Mastocytosis

Clinical guidelines for managing mast cell proliferative disorders, evaluating KIT D816V mutations, Darier's sign diagnostics, and reviewing antihi...

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Neurology5 min read

Cystic Fibrosis

Clinical guidelines for managing lung function, airway clearance, and utilizing CFTR modulators.

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Dermatology5 min read

Darier's Disease

Clinical guidelines for managing hereditary keratosis disorders, evaluating ATP2A2 mutations, SERCA2 calcium pump dysfunction, and reviewing oral r...

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Dermatology4 min read

Dermatitis Herpetiformis

Clinical guidelines for managing gluten-induced blistering disorders, evaluating epidermal transglutaminase and IgA papillary complexes, and review...

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Neurology4 min read

Dermatofibrosarcoma Protuberans (DFSP)

Clinical guidelines for managing dermal spindle cell sarcomas, evaluating COL1A1-PDGFB gene translocations, and reviewing Mohs micrographic surgery...

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Dermatology4 min read

Dermatomyositis

Clinical guidelines for managing autoimmune inflammatory myopathy, evaluating heliotrope rashes and perifascicular capillary MAC deposition, and re...

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Neurology5 min read

Discoid Lupus Erythematosus (DLE)

Clinical guidelines for managing chronic cutaneous lupus, evaluating type I interferon pathways, lupus band test diagnostics, and reviewing topical...

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Dermatology4 min read

Duchenne Muscular Dystrophy

Clinical guidelines for managing progressive muscle weakness, reviewing dystrophin genetic mutations, and evaluating novel exon-skipping and gene t...

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Neurology4 min read

Dyshidrotic Eczema

Clinical guidelines for managing pompholyx vesicles, identifying skin triggers, and topical JAK inhibitors.

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Dermatology3 min read

Eczema / Atopic Dermatitis

Clinical protocols for repairing the skin barrier and managing chronic inflammation.

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Neurology4 min read

Endometriosis

Clinical guidelines for managing pelvic pain, hormonal therapy, and excision surgery.

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Dermatology4 min read

Epidermolysis Bullosa

Clinical guidelines for managing genetic connective tissue disorders, evaluating collagen and laminin gene therapy, diagnostic antigen mapping, and...

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Neurology5 min read

Epilepsy

Clinical guidelines for managing seizure disorders, anti-epileptic medications, and advanced neuromodulation.

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Dermatology4 min read

Erythema Multiforme

Clinical guidelines for managing immune-mediated targetoid skin lesions, differentiating EM Minor vs Major, and evaluating HSV antiviral prophylaxis.

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Neurology4 min read

Erythema Nodosum

Clinical guidelines for managing septal panniculitis, identifying underlying systemic triggers, and pain relief strategies.

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Dermatology4 min read

Essential Tremor

Clinical guidelines for managing postural and kinetic tremors, evaluating cerebellar-thalamocortical circuitry and GABAergic signaling, and reviewi...

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Neurology4 min read

Friedreich's Ataxia

Clinical guidelines for managing inherited neurodegenerative ataxias, evaluating FXN GAA repeats and frataxin deficiency, and reviewing Omaveloxolo...

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Dermatology4 min read

Frontotemporal Dementia

Clinical guidelines for managing frontotemporal lobe degeneration, evaluating tau and TDP-43 neuropathology, MRI/PET diagnostics, and reviewing sym...

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Neurology4 min read

Generalized Anxiety Disorder

Clinical guidelines for managing chronic worry, somatic symptoms, and cognitive-behavioral interventions.

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Dermatology4 min read

Glioblastoma

Clinical guidelines for managing aggressive primary brain tumors, evaluating MGMT promoter methylation, EGFRvIII targeting, and reviewing the Stupp...

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Neurology4 min read

Granuloma Annulare

Clinical guidelines for managing localized and generalized annular papules, evaluating palisading granuloma pathology, and reviewing topical and sy...

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Dermatology5 min read

Guillain-Barre Syndrome (GBS)

Clinical guidelines for managing acute inflammatory demyelinating polyneuropathy, IVIG, and plasmapheresis.

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Neurology4 min read

Hailey-Hailey Disease (Benign Familial Pemphigus)

Clinical guidelines for managing inherited blistering disorders, evaluating ATP2C1 mutations and Golgi calcium dysregulation, and reviewing low-dos...

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Dermatology4 min read

Heart Failure

Clinical guidelines for managing reduced ejection fraction, fluid overload, and novel cardiac therapies.

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Neurology5 min read

Hereditary Spastic Paraplegia (HSP)

Clinical guidelines for managing inherited neurodegenerative disorders, evaluating SPG4 spastin mutations, microtubule transport axonal pathology, ...

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Dermatology4 min read

Hidradenitis Suppurativa

Clinical guidelines for managing chronic inflammatory skin conditions, evaluating follicular occlusion and TNF-α/IL-17 cytokine cascades, and...

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Neurology4 min read

Huntington's Disease

Clinical guidelines for managing progressive neurodegenerative diseases, evaluating CAG repeat expansions and striatal atrophy, and reviewing VMAT2...

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Dermatology4 min read

Hypertension

Clinical guidelines for managing high blood pressure, lifestyle interventions, and pharmacological therapies.

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Neurology4 min read

Ichthyosis Vulgaris

Clinical guidelines for managing keratinization disorders, evaluating FLG mutations and filaggrin/NMF deficiency, and reviewing humectants and barr...

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Dermatology5 min read

Idiopathic Intracranial Hypertension (IIH)

Clinical guidelines for managing elevated intracranial pressure, evaluating papilledema and lumbar puncture opening pressures, and reviewing Acetaz...

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Neurology4 min read

Keloids and Keloid Scars

Clinical guidelines for managing benign fibroproliferative growths, evaluating TGF-beta-mediated collagen deposition, and reviewing intralesional c...

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Dermatology4 min read

Keratosis Pilaris

Clinical guidelines for managing follicular hyperkeratosis, selecting keratolytic agents, and reviewing topical retinoid and laser therapies.

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Neurology4 min read

Lambert-Eaton Myasthenic Syndrome

Clinical guidelines for managing presynaptic neuromuscular disorders, evaluating P/Q-type calcium channel antibodies and paraneoplastic lung carcin...

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Dermatology4 min read

Lamellar Ichthyosis

Clinical guidelines for managing genetic keratinization disorders, evaluating TGM1 mutations, collodion membrane presentations, and reviewing topic...

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Neurology4 min read

Lewy Body Dementia

Clinical guidelines for managing alpha-synucleinopathies, evaluating cholinergic deficits, DaTscan diagnostics, and reviewing cholinesterase inhibi...

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Dermatology4 min read

Lichen Planopilaris

Clinical guidelines for managing primary cicatricial scarring alopecia, evaluating follicular stem cell damage, and reviewing local steroids, Hydro...

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Neurology4 min read

Lichen Planus

Clinical guidelines for managing T-cell mediated keratinocyte damage, distinguishing Wickham's striae, and reviewing mucosal immunomodulators.

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Dermatology4 min read

Lichen Sclerosus

Clinical guidelines for managing chronic inflammatory dermatoses, evaluating ECM1 autoantibodies and dermal homogenization, and reviewing Clobetaso...

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Neurology4 min read

Major Depressive Disorder

Clinical guidelines for managing depression, psychotherapy approaches, and novel interventional treatments.

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Dermatology4 min read

Melanoma

Clinical guidelines for managing cutaneous melanoma, understanding surgical margins, and reviewing targeted immunotherapies.

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Neurology4 min read

Melasma

Clinical guidelines for managing chronic facial hyperpigmentation, identifying hormonal triggers, and reviewing tyrosinase inhibitor therapies.

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Dermatology4 min read

Meniere's Disease

Clinical guidelines for managing fluctuating endolymphatic pressure, dietary sodium restriction, and intratympanic rescue therapies.

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Neurology4 min read

Meningitis

Clinical guidelines for managing meningeal inflammation, analyzing cerebrospinal fluid parameters, and evaluating rapid antibiotic and steroid prot...

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Dermatology5 min read

Migraine

Clinical guidelines for managing severe headaches, acute abortive therapies, and preventive strategies.

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Neurology4 min read

Morphea (Localized Scleroderma)

Clinical guidelines for managing localized fibrotic disorders, evaluating TGF-β signaling and myofibroblast collagen synthesis, and reviewing ...

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Dermatology4 min read

Multifocal Motor Neuropathy (MMN)

Clinical guidelines for managing immune-mediated motor neuropathies, evaluating anti-GM1 antibodies, motor conduction blocks, and reviewing IVIG an...

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Neurology4 min read

Multiple Sclerosis

Clinical guidelines for managing neuroinflammation and disease-modifying therapies.

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Dermatology4 min read

Multiple System Atrophy (MSA)

Clinical guidelines for managing atypical parkinsonian syndromes, evaluating oligodendrocytic α-synuclein GCIs and the hot cross bun sign, an...

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Neurology4 min read

Myasthenia Gravis

Clinical guidelines for managing autoimmune neuromuscular diseases, evaluating postsynaptic receptor antibodies and complement-mediated destruction...

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Dermatology4 min read

Mycosis Fungoides

Clinical guidelines for managing Cutaneous T-Cell Lymphoma, evaluating epidermotropism and Pautrier's microabscesses, and reviewing stage-based the...

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Neurology4 min read

Narcolepsy

Clinical guidelines for managing sleep-wake disorders, evaluating hypocretin/orexin neuron loss and HLA associations, and reviewing Modafinil and O...

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Dermatology4 min read

Netherton Syndrome

Clinical guidelines for managing severe congenital ichthyosis, evaluating SPINK5 mutations and LEKTI/kallikrein pathway dysregulation, and reviewin...

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Neurology4 min read

Neurofibromatosis

Clinical guidelines for managing neurocutaneous tumors, evaluating NF1/NF2 genetic parameters, and reviewing MEK inhibitor therapies.

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Dermatology5 min read

Neuromyelitis Optica (NMO)

Clinical guidelines for managing neuromyelitis optica spectrum disorder (NMOSD), relapse prevention, and targeted biologic treatments.

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Neurology4 min read

Neurosarcoidosis

Clinical guidelines for managing neuroinflammatory disorders, evaluating non-caseating granulomas, brain MRI and CSF diagnostics, and reviewing glu...

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Dermatology4 min read

Obsessive-Compulsive Disorder

Clinical guidelines for managing obsessions, compulsions, and exposure response therapies.

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Neurology4 min read

Osteoarthritis

Clinical guidelines for managing joint degeneration, pain, and mobility in Osteoarthritis.

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Dermatology4 min read

Osteoporosis

Clinical guidelines for managing bone mineral density, fall prevention, and anti-resorptive therapies.

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Neurology3 min read

Parkinson's Disease

Clinical guidelines for managing neurodegeneration and improving quality of life.

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Dermatology4 min read

Pemphigus Foliaceus

Clinical guidelines for managing autoimmune blistering disorders, evaluating Desmoglein 1 autoantibody diagnostics, direct immunofluorescence, and ...

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Neurology4 min read

Pemphigus Vulgaris

Clinical guidelines for managing life-threatening blistering diseases, evaluating desmoglein autoantibodies and acantholysis, and reviewing prednis...

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Dermatology4 min read

Pityriasis Alba

Clinical guidelines for managing atopic hypopigmented patches, evaluating epidermal barrier dysfunction, and reviewing topical emollient and anti-i...

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Neurology4 min read

Pityriasis Lichenoides

Clinical guidelines for managing PLEVA and PLC, evaluating wedge-shaped interface lymphocytic infiltrates, and reviewing immunomodulatory antibioti...

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Dermatology4 min read

Pityriasis Rosea

Clinical guidelines for managing acute Christmas-tree eruptions, evaluating HHV-6/HHV-7 viral reactivity, and reviewing acyclovir and phototherapy ...

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Neurology4 min read

Pityriasis Rotunda

Clinical guidelines for managing acquired circular scaling dermatoses, evaluating underlying malignancy and systemic associations, and reviewing to...

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Dermatology4 min read

Pityriasis Rubra Pilaris (PRP)

Clinical guidelines for managing progressive papulosquamous disorders, evaluating CARD14 mutations and NF-κB pathways, and reviewing Acitreti...

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Neurology4 min read

Pityriasis Versicolor

Clinical guidelines for managing superficial Malassezia yeast overgrowths, evaluating spaghetti-and-meatballs KOH scrapings, and reviewing topical ...

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Neurology4 min read

Plaque Psoriasis

Clinical guidelines for managing chronic autoimmune plaque lesions, identifying flare triggers, and utilizing targeted biologics.

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Dermatology4 min read

Porphyria Cutanea Tarda

Clinical guidelines for managing metabolic phototoxic disorders, evaluating UROD deficiency, plasma and urine porphyrin diagnostics, and reviewing ...

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Dermatology4 min read

Post-Traumatic Stress Disorder

Clinical guidelines for managing trauma, flashbacks, and evidence-based psychotherapies.

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Neurology4 min read

Primary Lateral Sclerosis (PLS)

Clinical guidelines for managing upper motor neuron disorders, evaluating precentral gyrus atrophy, EMG exclusion criteria, and reviewing muscle re...

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Dermatology4 min read

Progressive Multifocal Leukoencephalopathy (PML)

Clinical guidelines for managing JC-virus demyelinating diseases, evaluating oligodendrocyte lytic infection and white matter lesions, and reviewin...

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Neurology4 min read

Progressive Supranuclear Palsy (PSP)

Clinical guidelines for managing atypical parkinsonian syndromes, evaluating 4R tauopathies and hummingbird signs, and reviewing fall-prevention an...

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Dermatology4 min read

Prurigo Nodularis

Clinical guidelines for managing chronic itchy nodules, neuro-immune skin pathways, and targeted biologic treatments.

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Neurology4 min read

Pyoderma Gangrenosum

Clinical guidelines for managing painful necrotic ulcers, evaluating pathergy and IL-1β/TNF-α pathways, and reviewing systemic steroids ...

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Dermatology4 min read

Rasmussen's Encephalitis

Clinical guidelines for managing progressive unilateral inflammatory encephalopathy, evaluating CD8+ T-cell damage and Epilepsia Partialis Continua...

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Neurology4 min read

Restless Legs Syndrome

Clinical guidelines for managing Willis-Ekbom disease, screening for iron deficiency, and dopamine receptor agonist dosing.

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Dermatology4 min read

Rett Syndrome

Clinical guidelines for managing progressive neurodevelopmental disorders, evaluating MECP2 mutations and transcriptional silencing pathways, and r...

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Neurology4 min read

Rheumatoid Arthritis

Clinical guidelines for managing autoimmune joint inflammation, disease-modifying therapies, and preserving mobility.

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Dermatology4 min read

Rosacea

Clinical guidelines for managing chronic facial flushing, identifying vascular triggers, and reviewing targeted anti-inflammatory regimens.

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Neurology5 min read

Schizophrenia

Clinical guidelines for managing psychosis, positive and negative symptoms, and antipsychotic therapies.

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Neurology4 min read

Seborrheic Dermatitis

Clinical guidelines for managing chronic scaling of the scalp and face, evaluating Malassezia lipid metabolism, and reviewing antifungal and anti-i...

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Dermatology4 min read

Shingles (Herpes Zoster)

Clinical guidelines for managing shingles outbreaks, preventing postherpetic neuralgia, and vaccine schedules.

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Neurology4 min read

Small Fiber Neuropathy

Clinical guidelines for managing sensory and autonomic small-fiber neuropathies, evaluating intraepidermal nerve fiber density, QSART diagnostics, ...

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Dermatology5 min read

Spinal Cord Infarction (Spinal Stroke)

Clinical guidelines for managing ischemic spinal cord injuries, evaluating anterior spinal artery syndrome, owl's eye sign MRI, and reviewing perfu...

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Neurology4 min read

Spinal Muscular Atrophy

Clinical guidelines for managing motor neuron degeneration, evaluating SMN1/SMN2 gene parameters, and reviewing genetic splicing and gene transfer ...

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Dermatology5 min read

Stiff-Person Syndrome

Clinical guidelines for managing autoimmune movement disorders, evaluating GAD-65 antibody titers, EMG parameters, and reviewing GABAergic agonist ...

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Neurology4 min read

Sweet's Syndrome (Acute Febrile Neutrophilic Dermatosis)

Clinical guidelines for managing neutrophilic dermatoses, evaluating IL-1 receptor pathway activation, dermal neutrophilic infiltration, and review...

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Dermatology4 min read

Syringomyelia

Clinical guidelines for managing spinal cord fluid cavities, evaluating Chiari malformations and capelike dissociated sensory loss, and reviewing s...

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Neurology5 min read

Systemic Lupus Erythematosus

Clinical guidelines for managing flares, organ involvement, and novel biologic therapies in SLE.

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Dermatology4 min read

Systemic Sclerosis (Scleroderma)

Clinical guidelines for managing autoimmune connective tissue fibrosis, evaluating Anti-Scl-70 and centromere antibodies, nailfold capillaroscopy, ...

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Neurology4 min read

Tardive Dyskinesia

Clinical guidelines for managing neuroleptic-induced movement disorders, performing AIMS assessments, and reviewing VMAT2 inhibitor therapies.

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Dermatology4 min read

Tinea Versicolor

Clinical guidelines for managing superficial Malassezia fungal overgrowth, analyzing skin scrapings and fluorescent findings, and reviewing topical...

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Neurology4 min read

Tourette's Syndrome

Clinical guidelines for managing motor and vocal tics, evaluating CSTC circuit dysfunction, and reviewing CBIT behavioral training and dopaminergic...

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Dermatology4 min read

Transverse Myelitis

Clinical guidelines for managing acute spinal cord inflammation, immunotherapies, and long-term functional recovery.

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Neurology4 min read

Trigeminal Neuralgia

Clinical guidelines for managing neuropathic facial pain, evaluating microvascular decompression parameters, and reviewing sodium channel blockers.

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Dermatology4 min read

Tuberous Sclerosis Complex (TSC)

Clinical guidelines for managing multi-system hamartomatous disorders, evaluating TSC1/TSC2 mutations and mTORC1 pathways, and reviewing Everolimus...

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Neurology4 min read

Type 1 Diabetes

Clinical guidelines for managing autoimmune insulin deficiency and emerging treatments.

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Dermatology4 min read

Urticaria (Hives)

Clinical guidelines for managing acute and chronic spontaneous urticaria, antihistamine dosing, and biologic therapies.

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Neurology4 min read

Vitiligo

Clinical guidelines for managing autoimmune depigmentation, stabilizing active pigment loss, and evaluating targeted JAK inhibitors.

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Dermatology5 min read

Xeroderma Pigmentosum (XP)

Clinical guidelines for managing DNA repair deficiencies, evaluating nucleotide excision repair (NER) defects, and reviewing UV radiation avoidance...

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Medical Disclaimer: CareHub guides are provided for informational and patient educational purposes only and do not constitute medical advice, diagnosis, or treatment. Always consult a qualified physician before starting or modifying any therapy.

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