Entacapone (Comtan / Carbidopa-Levodopa-Entacapone Stalevo): Cost, CMS NADAC & Insurance Coverage
What it's for: Taken with each dose of levodopa/carbidopa to block peripheral COMT breakdown of levodopa, extending the duration of each levodopa dose ('ON' time). (Source: NINDS & FDA Prescribing Information)
Accuracy Level — Tier 1 Published Prices: You are currently viewing general published hospital cash prices, Medicare baselines, and multi-payer ranges. Add your insurance card to unlock Tier 2 plan pricing and Tier 3 verified benefit checks.
Cost Across Insurances Matrix for Entacapone
Hospital procedure cells are extracted from 14 Bay Area hospital MRFs (45 CFR § 180.50, Oct 2026); medication cells use CMS NADAC (as of 2026-10-28) & CY 2026 Medicare Part D / Medi-Cal Rx rules.
| Parkinson's Service / Medication | Self-Pay / Cash Price Hospital MRF / Retail Cash | Medicare Rate 2026 CMS / NADAC / Part D | Anthem Blue Cross MRF Negotiated / Formulary | Blue Shield of CA MRF Negotiated / Formulary | UnitedHealthcare MRF Negotiated / Formulary | Aetna MRF Negotiated / Formulary | Cigna MRF Negotiated / Formulary | Kaiser Permanente MRF Negotiated / Formulary | Medi-Cal (CA Medicaid) CA DHCS / Medi-Cal Rx |
|---|---|---|---|---|---|---|---|---|---|
MedicationNDC 00904682207 Entacapone (Comtan / Carbidopa-Levodopa-Entacapone Stalevo) | $28 – $95 / 30 days (120 generic entacapone tablets) $28 – $95 / 30 days (120 generic entacapone tablets); $75 – $185 / 30 days (120 generic Stalevo combination tablets) Source: CMS NADAC 2026 & Retail Pharmacy Cash Benchmarks (Oct 2026) Date: Oct 2026 | NADAC: $39.81 / 120 tablets (Entacapone) ENTACAPONE 200 MG TABLET ($0.33178/EA) & CARBIDOPA-LEVODOPA-ENTACAPONE 25-100-200 MG TAB ($0.69423/EA) • Medicare Part D patient cost: $5 – $42 copay / 30 days Source: CMS NADAC 2026 (data.medicaid.gov Dataset fbb83258-11c7-47f5-8b18-5f8e79f7e704) & CMS CY 2026 Medicare Part D Public Formulary File (Oct 2026) Date: 2026-10-28 | $5–$20 / 30d (Tier 1/2 Copay) Tier 2 Generic; no PA. (Covered CA 2026 standard generic copay design; plan-specific PBM net rebate price not publicly published) Source: Covered CA 2026 Standard Benefit Design & Anthem Blue Cross CA Commercial Formulary Date: Oct 2026 | $5–$20 / 30d (Tier 1/2 Copay) Tier 2 Generic; no PA. (Covered CA 2026 standard generic copay design; plan-specific PBM net rebate price not publicly published) Source: Covered CA 2026 Standard Benefit Design & Blue Shield of CA CA Commercial Formulary Date: Oct 2026 | $5–$20 / 30d (Tier 1/2 Copay) Tier 2 Generic; no PA. (Covered CA 2026 standard generic copay design; plan-specific PBM net rebate price not publicly published) Source: Covered CA 2026 Standard Benefit Design & UnitedHealthcare CA Commercial Formulary Date: Oct 2026 | $5–$20 / 30d (Tier 1/2 Copay) Tier 2 Generic; no PA. (Covered CA 2026 standard generic copay design; plan-specific PBM net rebate price not publicly published) Source: Covered CA 2026 Standard Benefit Design & Aetna CA Commercial Formulary Date: Oct 2026 | $5–$20 / 30d (Tier 1/2 Copay) Tier 2 Generic; no PA. (Covered CA 2026 standard generic copay design; plan-specific PBM net rebate price not publicly published) Source: Covered CA 2026 Standard Benefit Design & Cigna CA Commercial Formulary Date: Oct 2026 | $5–$20 / 30d (Tier 1/2 Copay) Formulary Generic; no PA. (Covered CA 2026 standard generic copay design; plan-specific PBM net rebate price not publicly published) Source: Covered CA 2026 Standard Benefit Design & Kaiser Permanente CA Commercial Formulary Date: Oct 2026 | $0 patient copay $0 copay on Medi-Cal Rx Contract Drug List. Source: CA DHCS Medi-Cal Rx Contract Drug List (CDL) & PA Policy Date: Oct 2026 |
National Average Drug Acquisition Cost (NADAC)
Medicare Part D Tier, Prior Auth & $2,100 Cap
Payer-by-Payer Formulary & Prior Authorization Notes
Tier 2 Generic; no PA.
Tier 2 Generic; no PA.
Tier 2 Generic; no PA.
Tier 2 Generic; no PA.
Tier 2 Generic; no PA.
Formulary Generic; no PA.
$0 copay on Medi-Cal Rx Contract Drug List.