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Non-Ergot Dopamine AgonistNDC: 68462033290 (0.5mg) / 13668018490 (0.75mg)

Pramipexole (Mirapex / Generic IR & ER): Cost, CMS NADAC & Insurance Coverage

What it's for: Directly stimulates striatal dopamine receptors (D2/D3) as monotherapy in early Parkinson's or as an adjunct to levodopa in advanced disease. (Source: NINDS & FDA Prescribing Information)

30-Day Retail Cash Range
$12 – $38 / 30 days (90 generic IR tablets); $95 – $240 / 30 days (generic ER)
Source: CMS NADAC 2026 & Retail Pharmacy Cash Benchmarks (Oct 2026)
CMS NADAC Baseline (As of 2026-10-28)
$4.95 – $5.85 / 90 tablets (30-day supply)
Per unit: $0.05497 – $0.06502 / tablet
2026 Medicare Part D Patient Cost
$0 – $12 copay / 30 days (IR)
Tier 1/2 (Generic IR); Tier 3/4 (Extended-Release ER)
1. Published Prices(Cash & Medicare)2. Plan-Adjusted(Payer MRF Rate)3. Verified Price(Real-Time 270/271 Check)

Accuracy Level — Tier 1 Published Prices: You are currently viewing general published hospital cash prices, Medicare baselines, and multi-payer ranges. Add your insurance card to unlock Tier 2 plan pricing and Tier 3 verified benefit checks.

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Cost Across Insurances Matrix for Pramipexole

Tier 1: General Published Rates Across 9 InsurancesEvery cell labeled with official Source + Date • “Not published” shown honestly where proprietary

Hospital procedure cells are extracted from 14 Bay Area hospital MRFs (45 CFR § 180.50, Oct 2026); medication cells use CMS NADAC (as of 2026-10-28) & CY 2026 Medicare Part D / Medi-Cal Rx rules.

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Parkinson's Service / Medication
Self-Pay / Cash Price
Hospital MRF / Retail Cash
Medicare Rate
2026 CMS / NADAC / Part D
Anthem Blue Cross
MRF Negotiated / Formulary
Blue Shield of CA
MRF Negotiated / Formulary
UnitedHealthcare
MRF Negotiated / Formulary
Aetna
MRF Negotiated / Formulary
Cigna
MRF Negotiated / Formulary
Kaiser Permanente
MRF Negotiated / Formulary
Medi-Cal (CA Medicaid)
CA DHCS / Medi-Cal Rx
MedicationNDC 68462033290
Pramipexole (Mirapex / Generic IR & ER)
Drug Guide →
$12 – $38 / 30 days (90 generic IR tablets)

$12 – $38 / 30 days (90 generic IR tablets); $95 – $240 / 30 days (generic ER)

Source: CMS NADAC 2026 & Retail Pharmacy Cash Benchmarks (Oct 2026)
Date: Oct 2026
NADAC: $4.95 – $5.85 / 90 tablets (30-day supply)

PRAMIPEXOLE 0.5 MG TABLET ($0.05497/EA) & PRAMIPEXOLE 0.75 MG TABLET ($0.06502/EA) • Medicare Part D patient cost: $0 – $12 copay / 30 days (IR)

Source: CMS NADAC 2026 (data.medicaid.gov Dataset fbb83258-11c7-47f5-8b18-5f8e79f7e704) & CMS CY 2026 Medicare Part D Public Formulary File (Oct 2026)
Date: 2026-10-28
$5–$20 / 30d (Tier 1/2 Copay)

Tier 1 Generic (IR); no PA. (Covered CA 2026 standard generic copay design; plan-specific PBM net rebate price not publicly published)

Source: Covered CA 2026 Standard Benefit Design & Anthem Blue Cross CA Commercial Formulary
Date: Oct 2026
$5–$20 / 30d (Tier 1/2 Copay)

Tier 1 Generic (IR); no PA. (Covered CA 2026 standard generic copay design; plan-specific PBM net rebate price not publicly published)

Source: Covered CA 2026 Standard Benefit Design & Blue Shield of CA CA Commercial Formulary
Date: Oct 2026
$5–$20 / 30d (Tier 1/2 Copay)

Tier 1 Generic (IR); no PA. (Covered CA 2026 standard generic copay design; plan-specific PBM net rebate price not publicly published)

Source: Covered CA 2026 Standard Benefit Design & UnitedHealthcare CA Commercial Formulary
Date: Oct 2026
$5–$20 / 30d (Tier 1/2 Copay)

Tier 1 Generic (IR); no PA. (Covered CA 2026 standard generic copay design; plan-specific PBM net rebate price not publicly published)

Source: Covered CA 2026 Standard Benefit Design & Aetna CA Commercial Formulary
Date: Oct 2026
$5–$20 / 30d (Tier 1/2 Copay)

Tier 1 Generic (IR); no PA. (Covered CA 2026 standard generic copay design; plan-specific PBM net rebate price not publicly published)

Source: Covered CA 2026 Standard Benefit Design & Cigna CA Commercial Formulary
Date: Oct 2026
$5–$20 / 30d (Tier 1/2 Copay)

Formulary Generic (IR); no PA. (Covered CA 2026 standard generic copay design; plan-specific PBM net rebate price not publicly published)

Source: Covered CA 2026 Standard Benefit Design & Kaiser Permanente CA Commercial Formulary
Date: Oct 2026
$0 patient copay

$0 copay on Medi-Cal Rx Contract Drug List (IR).

Source: CA DHCS Medi-Cal Rx Contract Drug List (CDL) & PA Policy
Date: Oct 2026
Official CMS NADAC Acquisition Cost Baseline

National Average Drug Acquisition Cost (NADAC)

Published Status: Published in CMS Retail Community Pharmacy Survey
NDC & Description: 68462033290 (0.5mg) / 13668018490 (0.75mg) — PRAMIPEXOLE 0.5 MG TABLET ($0.05497/EA) & PRAMIPEXOLE 0.75 MG TABLET ($0.06502/EA)
NADAC Per-Unit Rate: $0.05497 – $0.06502 / tablet
Typical 30-Day Regimen (0.5 mg or 0.75 mg tablet, 1 tablet 3 times daily (90 tablets / 30-day supply)): $4.95 – $5.85 / 90 tablets (30-day supply)
Effective Date / As-of Date: Effective 2026-10-21 (Verified as of 2026-10-28)
Source: CMS NADAC 2026 (data.medicaid.gov Dataset fbb83258-11c7-47f5-8b18-5f8e79f7e704)
CY 2026 Medicare Part D Formulary Rules

Medicare Part D Tier, Prior Auth & $2,100 Cap

Formulary Tier: Tier 1/2 (Generic IR); Tier 3/4 (Extended-Release ER)
Prior Authorization: No for generic IR; occasional Step Therapy for ER tablets
Step Therapy: No for IR
Quantity Limits: 90 tablets / 30 days (IR); 30 tablets / 30 days (ER)
2026 Patient Out-of-Pocket: $0 – $12 copay / 30 days (IR)
Source: CMS CY 2026 Medicare Part D Public Formulary File (Oct 2026)
California Commercial Payers & Medi-Cal Rx

Payer-by-Payer Formulary & Prior Authorization Notes

Anthem Blue Cross

Tier 1 Generic (IR); no PA.

Blue Shield of California

Tier 1 Generic (IR); no PA.

UnitedHealthcare (UHC)

Tier 1 Generic (IR); no PA.

Aetna

Tier 1 Generic (IR); no PA.

Cigna

Tier 1 Generic (IR); no PA.

Kaiser Permanente

Formulary Generic (IR); no PA.

Medi-Cal Rx (CA Medicaid)

$0 copay on Medi-Cal Rx Contract Drug List (IR).